Dichloromethane → 5-(4-(Chloromethyl)-2-methoxybenzyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

반응식

[Cl:30][CH2:31][Cl:32].[NH2:5][c:6]1[n:7][c:8]([NH:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[c:9]([CH2:13][c:14]2[c:15]([O:22][CH3:23])[cH:16][c:17]([CH2:20][OH:21])[cH:18][cH:19]2)[c:10]([CH3:12])[n:11]1.[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][CH2:20][c:17]1[cH:16][c:15]([O:22][CH3:23])[c:14]([CH2:13][c:9]2[c:8]([NH:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[n:7][c:6]([NH2:5])[n:11][c:10]2[CH3:12])[cH:19][cH:18]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 24386Thionyl Chloride

HCID 66819929(4-((2-Amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)-3-methoxyphenyl)methanol

생성물 1

HCID 689586835-(4-(Chloromethyl)-2-methoxybenzyl)-6-methyl-N4-pentylpyrimidine-2,4-diamine

출처 및 근거

ORD 기록: ord-856d1f0917f840f8b5ff2e2e4ebd9600
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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