Trifluoroacetic acid → N-(5-(5-(azetidin-3-ylmethyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

반응식

[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43].[n:1]1[cH:2][c:3]([C:10](=[O:11])[NH:12][c:13]2[cH:14][c:15](-[c:20]3[n:21][o:22][c:23]([CH2:25][CH:26]4[CH2:27][N:28]([C:30]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:36])[CH2:29]4)[n:24]3)[cH:16][cH:17][c:18]2[CH3:19])[n:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[n:1]1[cH:2][c:3]([C:10](=[O:11])[NH:12][c:13]2[cH:14][c:15](-[c:20]3[n:21][o:22][c:23]([CH2:25][CH:26]4[CH2:27][NH:28][CH2:29]4)[n:24]3)[cH:16][cH:17][c:18]2[CH3:19])[n:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 71281398Tert-butyl 3-((3-(3-(imidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methyl)azetidine-1-carboxylate

생성물 1

HCID 71281018N-(5-(5-(azetidin-3-ylmethyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

출처 및 근거

ORD 기록: ord-b4bccbfc3ba9486991f471e9bb97ed40
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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