Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → N-(2-Hydroxy-ethyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | 6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid | HCID 66599213 | — |
| 생성물 | N-(2-Hydroxy-ethyl)-6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinamide | HCID 57519926 | 81% |
반응 단계
As described for example 8b, 6-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-nicotinic acid (100 mg, 0.32 mmol) was converted, using ethanolamine instead of methylamine, to the title compound (92 mg, 81%) which was obtained as a white solid. MS: m/e=354.4 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846719B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-02d5c80aaf4141f7a7eebd6e37cb7404 |
| 출처 메모 | uspto-grants-2014_09 |