Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5-Dichlorothiophene-3-sulfonyl chloride → 1-[(2,5-Dichloro-3-thienyl)sulfonyl]-4-(1-piperazinyl)-1H-indole Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5-Dichlorothiophene-3-sulfonyl chloride | HCID 2736094 | — |
| 반응물 | tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate | HCID 22015386 | — |
| 생성물 | 1-[(2,5-Dichloro-3-thienyl)sulfonyl]-4-(1-piperazinyl)-1H-indole Hydrochloride | HCID 10226013 | — |
반응 단계
The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 2,5-dichloro-3-thienylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.24 (br, 1 H), 7.78 (d, J=5 Hz, 1 H), 7.72 (s, 1 H), 7.57 (d, J=8 Hz, 1 H), 7.29 (t, J=8 Hz, 1 H), 7.01 (d, J=5 Hz, 1 H), 6.86 (d, J=8 Hz, 1 H), 3.31 (m, 8 H). MS (ESI+) for m/z 416 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087750B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-ad9be4801a754d8082881cce7298696a |
| 출처 메모 | uspto-grants-2006_08 |