(1,1'-Biphenyl)-4-sulphonyl chloride → 1-([1,1'-Biphenyl]-4-yl-sulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride
반응식
C([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:22]=[CH:21][CH:20]=[C:19]3[C:15]=2[CH:16]=[CH:17][NH:18]3)[CH2:10][CH2:9]1)(OC(C)(C)C)=O.[C:23]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:28]=[CH:27][C:26]([S:29]([Cl:32])(=[O:31])=[O:30])=[CH:25][CH:24]=1>>[ClH:32].[C:23]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:28]=[CH:27][C:26]([S:29]([N:18]2[C:19]3[C:15](=[C:14]([N:11]4[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]4)[CH:22]=[CH:21][CH:20]=3)[CH:16]=[CH:17]2)(=[O:31])=[O:30])=[CH:25][CH:24]=1참가 물질
3
실험 절차
The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 1,1 ′-biphenyl-4-ylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.26 (br, 1H), 8.04 (m, 2 H), 7.88 (m, 3 H), 7.67 (m, 3 H), 7.46 (m, 3 H), 7.27 (t, J=8 Hz, 1 H), 6.96 (d, J=5 Hz, 1 H), 6.80 (d, J=8 Hz, 1 H), 3.25 (m, 8 H); MS (ESI+) for m/z 418 (M+H)+.
출처 및 근거
- ORD 기록
- ord-1abf8353d6f14c0799bcdf82ec791499
- 출처 데이터셋
- uspto-grants-2006_08