[1-(4-Fluoro-3-methoxy-benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid → [1-(3-Cyano-4-morpholin-4-yl-benzenesulfonyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-acetic acid

반응식

[CH3:27][O:28][C:29]([CH2:30][c:31]1[c:32]([CH3:57])[n:33]([S:40](=[O:41])(=[O:42])[c:43]2[cH:44][c:45]([C:55]#[N:56])[c:46]([N:49]3[CH2:50][CH2:51][O:52][CH2:53][CH2:54]3)[cH:47][cH:48]2)[c:34]2[n:35][cH:36][cH:37][cH:38][c:39]12)=[O:58].[F:1][c:2]1[cH:3][cH:4][c:5]([S:6]([n:7]2[c:8]3[n:9][cH:10][cH:11][cH:12][c:13]3[c:14]([CH2:15][C:16]([OH:17])=[O:18])[c:19]2[CH3:20])(=[O:21])=[O:22])[cH:23][c:24]1[O:25][CH3:26]>>[O:28]=[C:29]([CH2:30][c:31]1[c:32]([CH3:57])[n:33]([S:40](=[O:41])(=[O:42])[c:43]2[cH:44][c:45]([C:55]#[N:56])[c:46]([N:49]3[CH2:50][CH2:51][O:52][CH2:53][CH2:54]3)[cH:47][cH:48]2)[c:34]2[n:35][cH:36][cH:37][cH:38][c:39]12)[OH:58]