Dimethylformamide → 6-bromo-3-hydroxymethyl-2-(4-methanesulfonylbenzyl)-4-phenyl-2H-isoquinolin-1-one

반응식

[Br:6][c:7]1[cH:8][c:9]2[c:10](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:11]([C:29](=[O:30])[OH:31])[n:12]([CH2:18][c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[c:13](=[O:17])[c:14]2[cH:15][cH:16]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[Cl:38][C:39]([C:40]([Cl:41])=[O:42])=[O:43].[O:1]=[CH:2][N:3]([CH3:4])[CH3:5]>>[Br:6][c:7]1[cH:8][c:9]2[c:10](-[c:32]3[cH:33][cH:34][cH:35][cH:36][cH:37]3)[c:11]([CH2:29][OH:30])[n:12]([CH2:18][c:19]3[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[CH3:28])[cH:23][cH:24]3)[c:13](=[O:17])[c:14]2[cH:15][cH:16]1