7-Bromoisatin → 8-bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylic Acid

반응식

[Br:29][c:30]1[cH:31][cH:32][cH:33][c:34]2[c:35]1[NH:36][C:37](=[O:38])[C:39]2=[O:40].[C:41]([O:42][CH2:43][C:44](=[O:45])[CH2:46][c:47]1[cH:48][cH:49][c:50]([Cl:51])[cH:52][cH:53]1)(=[O:54])[CH3:55].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8][c:9]3[c:10](-[c:21]4[cH:22][cH:23][cH:24][cH:25][cH:26]4)[cH:11][cH:12][cH:13][c:14]3[c:15]([C:18](=[O:19])[OH:20])[c:16]2[OH:17])[cH:27][cH:28]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][c:7]2[n:8][c:9]3[c:10]([Br:29])[cH:11][cH:12][cH:13][c:14]3[c:15]([C:18](=[O:19])[OH:20])[c:16]2[OH:17])[cH:27][cH:28]1

참가 물질

반응물 3

HCID 23023537-Bromoisatin

HCID 113837082-(4-Chloro-benzyl)-3-hydroxy-8-phenyl-quinoline-4-carboxylic Acid

HCID 122224641-(Acetyloxy)-3-(4-chlorophenyl)-2-propanone

생성물 1

HCID 114861898-bromo-2-(4-chlorobenzyl)-3-hydroxyquinoline-4-carboxylic Acid

출처 및 근거

ORD 기록: ord-9b1ebe7f2bd141c4acf80cfef5d4e46b
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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