Dichloromethane → 4-Hydroxy-4-[5-(3-methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]piperidine-1-sulfonamide

반응식

[C:1]([O:2][C:3](=[O:4])[NH:7][S:8](=[O:9])(=[O:10])[N:11]1[CH2:12][CH2:13][C:14]([c:17]2[s:18][c:19](-[c:22]3[cH:23][c:24]([CH3:39])[cH:25][c:26]([NH:28][c:29]4[n:30][cH:31][cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[n:34]4)[cH:27]3)[cH:20][n:21]2)([OH:40])[CH2:15][CH2:16]1)([CH3:5])([CH3:6])[CH3:41].[Cl:49][CH2:50][Cl:51].[F:42][C:43]([F:44])([F:45])[C:46]([OH:47])=[O:48]>>[NH2:7][S:8](=[O:9])(=[O:10])[N:11]1[CH2:12][CH2:13][C:14]([c:17]2[s:18][c:19](-[c:22]3[cH:23][c:24]([CH3:39])[cH:25][c:26]([NH:28][c:29]4[n:30][cH:31][cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[n:34]4)[cH:27]3)[cH:20][n:21]2)([OH:40])[CH2:15][CH2:16]1