Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl Sulfoxide → 4-(2-Amino-4-methoxy-benzothiazol-7-yl)-1-methyl-piperazin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl Sulfoxide | HCID 679 | — |
| 반응물 | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| 반응물 | [2-Methoxy-5-(4-methyl-3-oxo-piperazin-1-yl)-phenyl]-thiourea | HCID 22015742 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 4-(2-Amino-4-methoxy-benzothiazol-7-yl)-1-methyl-piperazin-2-one | HCID 22015741 | — |
반응 단계
From [2-methoxy-5-(4-methyl-3-oxo-piperazin-1-yl)-phenyl]-thiourea with HBr—AcOH (4 equiv.) and DMSO (2.4 equiv.) in AcOH. ES-MS m/e (%): 293 (M+H+, 100).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087761B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-d179064351194b43a86982c843ec674b |
| 출처 메모 | uspto-grants-2006_08 |