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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 8361생성일: 2026년 10월 24일

2-[4-(3-Chloro-propoxy)-phenyl]-imidazo[1,2-a]pyridine → 2-[4-(3-Chloro-propoxy)-phenyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine

https://huagongshe.com/ko/reaction/8361

반응식

참여 물질

역할이름HCID투입량
반응물2-[4-(3-Chloro-propoxy)-phenyl]-imidazo[1,2-a]pyridineHCID 14097094—
촉매Adams' catalystHCID 345198—
용매EthanolHCID 702—
용매MethanolHCID 887—
생성물2-[4-(3-Chloro-propoxy)-phenyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridineHCID 2201562796.4%

반응 단계

To a Parr bottle charged with a mixture of platinum (IV) oxide (30 mg) in ethanol (3 mL) was added a solution of the product of Step A (90 mg) in methanol (6 ml). The mixture was hydrogenated at 40 psi for 4 hours and filtered through a Celite pad which was rinsed with several additional milliliters of methanol and ethanol. The filtrate was collected and evaporated in vacuo to yield the title compound (88 mg) which was used without further purification.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07087757B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-838c0cefe9b94edaae563cc0b0c31601
출처 메모uspto-grants-2006_08