Tert-butyl 3-(2-methyl-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate → 2-Methyl-4-(pyrrolidin-3-yl)-1,3-thiazole

반응식

[CH3:13][c:14]1[s:15][cH:16][c:17]([CH:19]2[CH2:20][N:21]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:22][CH2:23]2)[n:18]1.[F:1][c:2]1[cH:3][n:4][cH:5][c:6]([CH:7]2[CH2:8][CH2:9][NH:10][CH2:11]2)[cH:12]1.[F:31][c:32]1[cH:33][c:34]([CH:35]2[CH2:36][CH2:37][N:38]([C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[CH2:46]2)[cH:47][n:48][cH:49]1>>[CH3:13][c:14]1[s:15][cH:16][c:17]([CH:19]2[CH2:20][NH:21][CH2:22][CH2:23]2)[n:18]1

참가 물질

반응물 3

HCID 53429459Tert-butyl 3-(2-methyl-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate

HCID 58408449HCID 58408449, 화합물

HCID 58408478Tert-butyl 3-(5-fluoropyridin-3-yl)pyrrolidine-1-carboxylate

생성물 1

HCID 534291712-Methyl-4-(pyrrolidin-3-yl)-1,3-thiazole

출처 및 근거

ORD 기록: ord-d351585d034e4b36916b57c6dcbdac4e
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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