Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-4-methylpyridine → 2-(4-Bromophenyl)-7-methylimidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-4-methylpyridine | HCID 1533 | — |
| 반응물 | 4-Bromophenacyl bromide | HCID 7454 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-(4-Bromophenyl)-7-methylimidazo[1,2-a]pyridine | HCID 717644 | 56.8% |
반응 단계
A mixture of 2,4′-dibromoacetophenone (22.4 g) and 2-amino-4-picoline (8.68 g) in ethanol (80 mL) was heated at reflux temperature for 3 hours. The reaction mixture was cooled to ambient temperature and the crystalline solid isolated by filtration, washed with ethanol and dried in vacuo to give the title compound (13.1 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087757B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-e6db157d18cf461c8d370ac086ebe049 |
| 출처 메모 | uspto-grants-2006_08 |