p-Toluenesulfonic acid → TsOH MTBD
반응식
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:6][CH:7]=1.[CH3:12][N:13]1[C:18]2=[N:19][CH2:20][CH2:21][CH2:22][N:17]2[CH2:16][CH2:15][CH2:14]1>CCOCC>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:12][N:13]1[C:18]2=[N:19][CH2:20][CH2:21][CH2:22][N:17]2[CH2:16][CH2:15][CH2:14]1참가 물질
4
실험 절차
A flame dried flask was charged with TsOH (0.28 g, 1.63 mmol), ether (20 mL) and a stirbar under dry nitrogen atmosphere. To the stirred solution, MTBD (0.25 g, 1.63 mmol) was added. Instantly, a white precipitate formed and stirring was continued for 1 hour. The precipitate, 0.47 g (88%) of white salt, was then washed with excess ether and isolated by decantation. The salt was then dried under high vacuum.
후처리
- custom