Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4'-Hydroxyacetophenone → 2-Bromo-1-(4-hydroxyphenyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4'-Hydroxyacetophenone | HCID 7469 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-Bromo-1-(4-hydroxyphenyl)ethanone | HCID 4964 | — |
반응 단계
4-Acetylphenol (20 g) in ether (200 mL) was treated with bromine (6.8 mL) and stirred at ambient temperature for 18 hours. The solution was poured into saturated sodium bicarbonate, stirred for 30 minutes and the organic layer separated. The organic portion was washed with saturated sodium bicarbonate, dried over magnesium sulfate, filtered and evaporated to afford the title compound (30 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087757B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-c56bedb66ea340c2b3e2c3252be8914e |
| 출처 메모 | uspto-grants-2006_08 |