1-(2-Aminobenzothiazol-6-yl)-3-(4-chloro-3-trifluoromethylphenyl)urea → 1-(4-Chloro-3-trifluoromethyl-phenyl)-3-[2-(7-hydroxy-6-methoxy-quinazolin-4-ylamino)-benzothiazol-6-yl]-urea

반응식

[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[NH2:15][c:16]1[s:17][c:18]2[c:19]([n:20]1)[cH:21][cH:22][c:23]([NH:25][C:26](=[O:27])[NH:28][c:29]1[cH:30][c:31]([C:36]([F:37])([F:38])[F:39])[c:32]([Cl:35])[cH:33][cH:34]1)[cH:24]2>>[c:2]1([NH:15][c:16]2[s:17][c:18]3[c:19]([n:20]2)[cH:21][cH:22][c:23]([NH:25][C:26](=[O:27])[NH:28][c:29]2[cH:30][c:31]([C:36]([F:37])([F:38])[F:39])[c:32]([Cl:35])[cH:33][cH:34]2)[cH:24]3)[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12

참가 물질

반응물 2

HCID 231325021-(2-Aminobenzothiazol-6-yl)-3-(4-chloro-3-trifluoromethylphenyl)urea

HCID 1357422514-Chloro-6-methoxyquinazolin-7-ol

생성물 1

HCID 1360721651-(4-Chloro-3-trifluoromethyl-phenyl)-3-[2-(7-hydroxy-6-methoxy-quinazolin-4-ylamino)-benzothiazol-6-yl]-urea

출처 및 근거

ORD 기록: ord-22050a3509834ad4a723f0c397521299
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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