Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-(1-Pyrrolidinyl)-4-phenoxy-4-sulphamylbenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Piretanide | HCID 4849 | — |
| 반응물 | 3-(1-Pyrrolidinyl)-4-phenoxy-5-aminobenzoic acid | HCID 21312072 | — |
| 반응물 | 3-(1-Pyrrolidinyl)-4-phenoxy-5-chlorosulphonyl-benzoic acid | HCID 21312108 | — |
| 생성물 | 3-(1-Pyrrolidinyl)-4-phenoxy-4-sulphamylbenzoic acid | HCID 70606662 | — |
반응 단계
The hydrochloride of the 3 -(1-pyrrolidinyl)-4-phenoxy-5-aminobenzoic acid is converted in the manner described in Example 35 over the 3-(1-pyrrolidinyl)-4-phenoxy-5-chlorosulphonyl-benzoic acid into the desired 3-(1-pyrrolidinyl)-4-phenoxy-5-sulphamylbenzoic acid melting at 225°-226° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04093735 |
| 출처 데이터셋 | uspto-grants-1978_06 |
| ORD ID | ord-f2a6bdb43bf042c181ca88dd7280fad4 |
| 출처 메모 | uspto-grants-1978_06 |