Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → Methyl 3-aminosulfonyl-4-phenoxy-5-(1-pyrrolidinyl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Piretanide | HCID 4849 | — |
| 생성물 | Methyl 3-aminosulfonyl-4-phenoxy-5-(1-pyrrolidinyl)benzoate | HCID 11545297 | — |
반응 단계
36.2 g of 4-phenoxy-3-(1-pyrrolidinyl)-5-sulphamoylbenzoic acid are dissolved in 200 ml of methanol and 7 ml of concentrated H2SO4 and heated for 4 to 6 hours under reflux. Upon cooling, the ester crystallises. Recrystallisation from methanol; M.p. 191° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04093735 |
| 출처 데이터셋 | uspto-grants-1978_06 |
| ORD ID | ord-a417afc60db24b19bea783b3d50dc545 |
| 출처 메모 | uspto-grants-1978_06 |