5-(Benzyloxy)-2-diazonio-1-methoxy-3-oxohepta-1,6-dien-1-olate → HCID 53869755, 화합물

HRID 839277노트

반응식

HRID 839277 반응식
[CH3:1][O:2][C:3](=[O:21])[C:4](=[N+]=[N-])[C:5](=[O:18])[CH2:6][CH:7]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH:8]=[CH2:9]>C1(C)C(C)=CC=CC=1>[CH3:1][O:2][C:3]([C:4]12[CH2:9][CH:8]1[CH:7]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:6][C:5]2=[O:18])=[O:21]

참가 물질

3

반응물 1

HCID 540398955-(Benzyloxy)-2-diazonio-1-methoxy-3-oxohepta-1,6-dien-1-olate

생성물 1

HCID 53869755HCID 53869755, 화합물수율 23.8%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

In accordance with the process of Preparation 22, 5-benzyloxy-2-diazo-3-oxo-6-heptenoic acid methyl ester (1.16 g; 4 mmol) and copper acetylacetone complex (100 mg) were dissolved in 30 ml of anhydrous xylene. The reaction product was purified by silica gel column chromatography to obtain two types of isomers of 4-benzyloxy-2-oxo-bicyclo[3.1.0] hexane-1-carboxylic acid methyl ester (248mg) as an oily product.

후처리

  1. customThe reaction product was purified by silica gel column chromatography

출처 및 근거

ORD 기록
ord-ba22bac3efe54a6bb169f74dee7473b0
출처 데이터셋
uspto-grants-1978_06
특허 번호
US04094886

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