Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → HCID 20323300, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,2,3,3a,5,6,10b,11,12,12a-Decahydrobenzo[a]cyclopenta[f]quinolizin-12-one | HCID 20323296 | — |
| 반응물 | HCID 178511344 | HCID 178511344 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 20323300 | HCID 20323300 | — |
반응 단계
According to the general procedure of J. W. Huffman and P. G. Arapakos, J. Org. Chem. 30, 1604 (1965) 10.0 g (0.042 mole) of 1,2,3,3a,5,6,10b,11,12,12a-decahydrobenzo[a]cyclopenta[f]quinolizin-12-one in 50 ml of tetrahydrofuran is reacted with an excess of lithium acetylide-ethylenediamine. The resulting material is dissolved in ether and treated with excess ethereal hydrochloric acid, and the precipitate is recrystallized from butanone-methanol to give 12-ethynyl-1,2,3,3a,5,6,10b, 11,12,12a-decahydrobenzo[a]cyclopenta[f]quinolizin-12-ol hydrochloride, M.P. 230°-240° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04096147 |
| 출처 데이터셋 | uspto-grants-1978_06 |
| ORD ID | ord-078eeef89c514c65b9b4796fd8c94066 |
| 출처 메모 | uspto-grants-1978_06 |