Triethylamine → HCID 20322099, 화합물

HRID 839818노트

반응식

HRID 839818 반응식
[CH3:1][O:2][CH:3]([O:6][CH2:7][CH3:8])[CH2:4][NH2:5].Br[CH2:10][CH:11]1[O:16][CH2:15][CH2:14][CH2:13][O:12]1.C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:15][O:16][CH:11]([O:12][CH2:13][CH3:14])[CH2:10][NH:5][CH2:4][CH:3]1[O:2][CH2:1][CH2:8][CH2:7][O:6]1

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 3036832-Bromomethyl-1,3-dioxaneHCID 22766278HCID 22766278, 화합물

생성물 1

HCID 20322099HCID 20322099, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

2-Methoxy-2-ethoxyethylamine (0.11 mole), 2-bromomethyl-1,3-dioxane (0.1 mole), triethylamine (20 ml) and toluene (150 ml) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction is heated at reflux for a period of about 12 hours. After this time the reaction mixture is allowed to cool to room temperature and is filtered. The reaction mixture is then stripped of solvent and unreacted starting materials under reduced pressure to yield the desired product N-(2-methoxy-2-ethoxyethyl)-N-(1,3-dioxan-2-ylmethyl)amine.

후처리

  1. customequipped with a mechanical stirrer
  2. temperaturethermometer and reflux condenser
  3. temperatureThe reaction is heated
  4. temperatureat reflux for a period of about 12 hours
  5. filtrationis filtered

출처 및 근거

ORD 기록
ord-c9b116a5d4b644b2bf48d3fc72a38d25
출처 데이터셋
uspto-grants-1978_06
특허 번호
US04097491

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