Acetone → 2,6,6-Trimethylfulvene

HRID 840998

반응식

HRID 840998 반응식
C[Li].[CH3:3][C:4]1[CH2:8][CH:7]=[CH:6][CH:5]=1.[CH3:9][C:10]([CH3:12])=O>>[CH3:3][C:4]1[CH:8]=[CH:7][C:6](=[C:10]([CH3:12])[CH3:9])[CH:5]=1

참가 물질

4

반응물 3

HCID 180AcetoneHCID 667751-Methyl-1,3-cyclopentadieneHCID 178418348HCID 178418348, 화합물

생성물 1

HCID 143632822,6,6-Trimethylfulvene수율 85%

반응 조건

온도
25 °C

실험 절차

150 ml of methylcyclopentadiene dimer was fractionally distilled from 100 ml of mineral oil and at 62° C. and collected at 0° C. 500 mmol of methyl lithium (1.4M; diethylether) were added, dropwise, to a mixture of 500 mmol of freshly distilled methylcyclopentadiene and 137 ml of dry acetone at 0° C. The solution was stirred for 1 hour at 25° C. 8 g (85% yield) of 3,6,6-trimethylfulvene were recovered from the organic layer by vacuum distillation after an extraction with 100 ml of saturated, aqueous NH4Cl and drying over MgSO4.

후처리

  1. distillation150 ml of methylcyclopentadiene dimer was fractionally distilled from 100 ml of mineral oil and at 62° C.
  2. customcollected at 0° C

출처 및 근거

ORD 기록
ord-20b182c62190448db407410b46b4ebaf
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06369175B1

연결된 노트

불러오는 중…