6-Chloro-2-(piperazin-1-yl)-1,3-benzoxazole → HCID 67609541, 화합물

HRID 84168

반응식

HRID 84168 반응식
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]3)[O:8][C:4]=2[CH:3]=1.[N:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[S:23]([NH:26][C:27]1[CH:35]=[CH:34][C:30]([C:31](O)=[O:32])=[CH:29][CH:28]=1)(=[O:25])=[O:24]>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]2[N:6]=[C:7]([N:9]3[CH2:14][CH2:13][N:12]([C:31]([C:30]4[CH:29]=[CH:28][C:27]([NH:26][S:23]([C:18]5[CH:19]=[CH:20][CH:21]=[CH:22][N:17]=5)(=[O:25])=[O:24])=[CH:35][CH:34]=4)=[O:32])[CH2:11][CH2:10]3)[O:8][C:4]=2[CH:3]=1

참가 물질

3

반응물 2

HCID 252190786-Chloro-2-(piperazin-1-yl)-1,3-benzoxazoleHCID 694094624-(Pyridine-2-sulfonylamino)benzoic acid

생성물 1

HCID 67609541HCID 67609541, 화합물

실험 절차

Compound 14 is prepared using synthesis method 2 using intermediates 3b and 5c (yield: 56%).

출처 및 근거

ORD 기록
ord-fca130b3a5884313b0e8fcdff6816a8e
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846930B2

연결된 노트

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