Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Aminobenzamide → 1-(3-Carbamoylphenyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Aminobenzamide | HCID 1645 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Ethyl 2-acetyl-4-oxo-4-phenylbutanoate | HCID 312893 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(3-Carbamoylphenyl)-2-methyl-5-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester | HCID 9946286 | — |
반응 단계
3-Aminobenzamide (5 mmol, 1.0 g), 3-oxo-2-(2-oxo-2-phenyl-ethyl)-butyric acid ethyl ester (5 mmol, 1.2 g), and tosic acid (0.1 g) were combined in ethanol, then heated under reflux. The resulting precipitate was filtered from the mixture, then washed with ethanol. The white solid product was used without further purification (m.p. 237.8° C.-238.8° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06372777B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-73c5fb46af684ac0bc7b85342b24b8d8 |
| 출처 메모 | uspto-grants-2002_04 |