Diethyl methylmalonate → Diethyl 2-(2-(2-benzyloxyphenyl)ethyl)-2-methylmalonate

반응식

[CH3:1][CH2:2][O:3][C:4]([CH:6]([C:8]([O:10][CH2:11][CH3:12])=[O:9])[CH3:7])=[O:5].[CH2:13]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28]I)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[CH2:27][CH2:28][C:6]([CH3:7])([C:4]([O:3][CH2:2][CH3:1])=[O:5])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

반응물 2

HCID 11857Diethyl methylmalonate

HCID 226187172-(2-Benzyloxyphenyl)ethyl iodide

생성물 1

HCID 22618873Diethyl 2-(2-(2-benzyloxyphenyl)ethyl)-2-methylmalonate

실험 절차

2-Methylmalonic acid diethyl eater and 2-(2-benzyloxyphenyl)ethyl iodide were used in the same manner as working example 52 (S) to give the subject compound.

후처리

customto give the subject compound

출처 및 근거

ORD 기록: ord-e20db442b6b2485e9a0f15ea1522f38d
출처 데이터셋: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06372800B1

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