Water → Furan-2-acetic acid

HRID 842302

반응식

HRID 842302 반응식
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]#N.[OH-:9].[K+].[OH2:11]>>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]([OH:11])=[O:9]

참가 물질

4

반응물 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 109095152-Furanacetonitrile

생성물 1

HCID 75974Furan-2-acetic acid

실험 절차

A mixture of 2-furanacetonitrile (6.14 g), KOH (4.0 g), and water (25 mL) was refluxed for 1 hour and then cooled. Following extraction with ether, the aqueous layer was acidified to pH 2.0 with concentrated aqueous HCl. This solution was extracted with ether, and the organic phase was dried over MgSO4 and evaporated under vacuum to yield 2-furanacetic acid. The structure of the product was confirmed by NMR.

후처리

  1. temperaturewas refluxed for 1 hour
  2. temperaturecooled
  3. extractionextraction with ether
  4. extractionThis solution was extracted with ether
  5. dry with materialthe organic phase was dried over MgSO4
  6. customevaporated under vacuum

출처 및 근거

ORD 기록
ord-e04ded5e86414da0b6241c4fcbfbb6f8
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06372895B1

연결된 노트

불러오는 중…