4-(3,5-Dimethylphenyl)-2-isopropylindene → Lithium 4-(3,5-dimethylphenyl)-2-isopropylindenide

HRID 842476노트

반응식

HRID 842476 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH:11]=[C:12]([CH:18]([CH3:20])[CH3:19])[CH2:13]3)[CH:5]=[C:6]([CH3:8])[CH:7]=1.[Li:21]CCCC>CCCCC>[CH3:8][C:6]1[CH:5]=[C:4]([C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH:11]=[C:12]([CH:18]([CH3:20])[CH3:19])[CH-:13]3)[CH:3]=[C:2]([CH3:1])[CH:7]=1.[Li+:21]

참가 물질

4

반응물 2

HCID 220230144-(3,5-Dimethylphenyl)-2-isopropylindeneHCID 178418339Butyllithium

생성물 1

HCID 22023013Lithium 4-(3,5-dimethylphenyl)-2-isopropylindenide

시약·촉매·용매 1

HCID 8003Pentane용매

실험 절차

4-(3′,5′-dimethylphenyl)-2-isopropylindene (5.5 g, 21 mmol) was dissolved in 80 mL of pentane. To this solution was added 8.3 mL of n-BuLi (2.5M in hexane) and the reaction was allowed to stir 4 hours at room temperature. A white solid precipitated from solution and was collected by frit filtration and washed with additional pentane. Yield was 3.3 g (60%).

후처리

  1. customA white solid precipitated from solution
  2. filtrationwas collected by frit filtration
  3. washwashed with additional pentane

출처 및 근거

ORD 기록
ord-3def1867ec7944cbbca7c329ffe7a33a
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06376411B1

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