9,9-Dichloro-9-silafluorene → 4-(3',5'-Bis-[t-butyl]phenyl)2-isopropylindene

HRID 842482노트

반응식

HRID 842482 반응식
Cl[Si]1(Cl)C2C=CC=CC=2C2C1=CC=CC=2.[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH:39]([CH3:41])[CH3:40])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:19])([CH3:18])[CH3:17].[Li]>C1COCC1>[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH:39]([CH3:41])[CH3:40])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:17])([CH3:18])[CH3:19]

참가 물질

4

반응물 2

HCID 6195839,9-Dichloro-9-silafluoreneHCID 69683378Lithium 4-(3',5'-di-t-butylphenyl)-2-isopropylindene

생성물 1

HCID 220230714-(3',5'-Bis-[t-butyl]phenyl)2-isopropylindene

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

9,9-Dichloro-9-silafluorene (1.1 g, 8.5 mmol) was dissolved in 80 mL of THF. To this solution was slowly added lithium 4-(3′,5′-di-t-butylphenyl)-2-isopropylindene (3.0 g, 8.5 mmol) as a dry powder and the solution was stirred overnight. After this time, the solvent was removed in vacuo and the residue was taken up in diethyl ether. The solution as filtered through frit to remove LiC and the solvent was removed in vacuo and used as a crude product (3.9 g) for the next step.

후처리

  1. customAfter this time, the solvent was removed in vacuo
  2. filtrationThe solution as filtered through frit
  3. customto remove LiC
  4. customthe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-1d9e73d314d94b9cabf6525ff6e8b898
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06376412B1

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