9,9-Dichloro-9-silafluorene → 4-(3',5'-Di-t-butylphenyl)-2-methylindene

HRID 842525노트

반응식

HRID 842525 반응식
Cl[Si]1(Cl)C2C=CC=CC=2C2C1=CC=CC=2.[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH3:39])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:19])([CH3:18])[CH3:17].[Li]>C1COCC1>[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH3:39])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:17])([CH3:18])[CH3:19]

참가 물질

4

반응물 2

HCID 6195839,9-Dichloro-9-silafluoreneHCID 69684158Lithium 4(3',5'-di-t-butylphenyl)-2-methylindene

생성물 1

HCID 120107434-(3',5'-Di-t-butylphenyl)-2-methylindene

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

9,9-Dichloro-9-silafluorene (1.2 g, 9.2 mmol) was dissolved in 80 mL of THF. To this solution was slowly added lithium 4-(3′,5′-di-t-butylphenyl)-2-methylindene (3.0 g, 9.2 mmol) as a dry powder and the solution was stirred overnight. After this time, the solvent was removed in vacuo and the residue was taken up in diethyl ether. The solution was filtered through a frit to remove LiCl and the solvent was removed in vacuo and used as a crude product (4.1 g) for the next step.

후처리

  1. customAfter this time, the solvent was removed in vacuo
  2. filtrationThe solution was filtered through a frit
  3. customto remove LiCl
  4. customthe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-b626c022c27c442c8611afc748d9d435
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06376407B1

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