Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-Chloro-2-cyanopyrazine 1-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 3-Chloropyrazine-2-carbonitrile | HCID 292465 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 3-Chloro-2-cyanopyrazine 1-oxide | HCID 10796992 | — |
반응 단계
2-Chloro-3-cyanopyrazine (5.00 g, 35.94 mmol) in concentrated H2SO4 (35 mL) at 0° C. was treated portionwise with K2S2O8 (11.65 g, 43.95 mmol), warmed to room temperature, stirred for 24 hours, treated with water, and extracted with chloroform. The organic extract was washed sequentially with water, saturated NaHCO3 and brine, dried (MgSO4) and concentrated to provide the title compound. MS (DCI/NH3) m/e 173 (M+NH4)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06376488B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-aff5277d64c849fdb0f118686d72d8e9 |
| 출처 메모 | uspto-grants-2002_04 |