참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 2-Chloropyridine-3,5-dicarbonitrile | HCID 10986579 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-amino-1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile | HCID 178510334 | — |
반응 단계
Hydrazine hydrate (55%, 125 μL, 2.20 mmol) was added to a stirred suspension of 2-chloro-3,5-dicyanopyridine (240 mg, 1.47 mmol) and triethylamine (205 μL, 1.47 mmol) in ethanol (3 mL) and the resulting red mixture was heated to 60° C. After 16 h the mixture was cooled and filtered to give the title compound:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06376499B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_04 |
|---|
| ORD ID | ord-7bac2a1c9f9e468fa8fa8cecea7a7103 |
|---|
| 출처 메모 | uspto-grants-2002_04 |
|---|
