Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quinoline → Quinoline 1-oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quinoline | HCID 7047 | — |
| 반응물 | m-Chloroperbenzoic acid | HCID 70297 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Quinoline 1-oxide | HCID 15366 | 90% |
반응 단계
To a 100 mL round bottom flask containing a solution of quinoline (12.2 mmol) in 50 mL of DCM was added 5.3 g of m-CPBA (30.6 mmol). The reaction mixture was stirred for 24 h. The reaction mixture was then diluted DCM (100 mL), washed with 5% NaOH (2×100 mL), dried (MgSO4), filtered, and concentrated in vacuo to give solid quinoline-N-oxide (90-95% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06376670B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-8904fd4023974a40b9824f645aa4ca6c |
| 출처 메모 | uspto-grants-2002_04 |