Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(S)-Cyclohex-1-enyl-hydroxy-phenyl-acetic acid → Cyclohexylphenylglycolic acid, (+)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (S)-Cyclohex-1-enyl-hydroxy-phenyl-acetic acid | HCID 10585664 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Cyclohexylphenylglycolic acid, (+)- | HCID 777375 | 91% |
반응 단계
To a solution of (S)-Cyclohexenyl phenyl glycolic acid (1.11 g, 4.78 mmol) in methanol (16 mL) was added 10% Pd/C (0.11 g). The reaction was subjected to 1 ATM of Hydrogen and was allowed to stir for 18 h. the reaction mixture was filtered through a plug of celite and concentrated in vacuo to provide 1.01 g of (S)-CHPGA (91%, 98.3% e.e.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06376684B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-eda513b977ac4ffe8c2d34e66594a125 |
| 출처 메모 | uspto-grants-2002_04 |