Tributylstannane → Bis[1-(2-hydroxypropoxy)-2,2,6,6-tetramethylpiperidin-4-yl]Sebacate

HRID 843475

반응식

HRID 843475 반응식
[CH2:1]([SnH](CCCC)CCCC)[CH2:2][CH2:3]C.Br[CH2:15][CH:16]([OH:18])[CH3:17].[C:19]([O:43][CH:44]1[CH2:49][C:48]([CH3:51])([CH3:50])[N:47]([OH:52])[C:46]([CH3:54])([CH3:53])[CH2:45]1)(=[O:42])[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O:30][CH:31]1[CH2:36][C:35]([CH3:38])([CH3:37])[N:34]([OH:39])[C:33]([CH3:41])([CH3:40])[CH2:32]1)=[O:29].CCCCCCC.CCCCCCC.C(OCC)(=[O:71])C>ClC1C=CC=CC=1>[OH:18][CH:16]([CH3:17])[CH2:15][O:39][N:34]1[C:33]([CH3:40])([CH3:41])[CH2:32][CH:31]([O:30][C:28](=[O:29])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][C:19]([O:43][CH:44]2[CH2:45][C:46]([CH3:54])([CH3:53])[N:47]([O:52][CH2:1][CH:2]([OH:71])[CH3:3])[C:48]([CH3:51])([CH3:50])[CH2:49]2)=[O:42])[CH2:36][C:35]1([CH3:37])[CH3:38]

참가 물질

7

반응물 5

HCID 5948TributylstannaneHCID 8900HeptaneHCID 297401-Bromo-2-propanolHCID 11272241Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioateHCID 21899848Ethylacetate heptane

생성물 1

HCID 22507677Bis[1-(2-hydroxypropoxy)-2,2,6,6-tetramethylpiperidin-4-yl]Sebacate

시약·촉매·용매 1

HCID 7964Chlorobenzene용매

실험 절차

Tributyltin hydride is added dropwise to a solution of 1-bromo-2-propanol and excess bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl) sebacate in chlorobenzene. The mixture is heated to facilitate reaction. The crude reaction mixture is passed through silica gel with heptane and then heptane/ethyl acetate to afford the title compound.

후처리

  1. temperatureThe mixture is heated
  2. customreaction
  3. customThe crude reaction mixture

출처 및 근거

ORD 기록
ord-78c057424f494d35afa53fb3e7d2abb6
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06376584B1

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