9,9-Dichloro-9-silafluorene → 4-(3',5'-Bis-[t-butyl]phenyl)2-isopropylindene

HRID 843529노트

반응식

HRID 843529 반응식
Cl[Si]1(Cl)C2C=CC=CC=2C2C1=CC=CC=2.[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH:39]([CH3:41])[CH3:40])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:19])([CH3:18])[CH3:17].[Li]>C1COCC1>[C:16]([C:20]1[CH:21]=[C:22]([C:30]2[CH:38]=[CH:37][CH:36]=[C:35]3[C:31]=2[CH:32]=[C:33]([CH:39]([CH3:41])[CH3:40])[CH2:34]3)[CH:23]=[C:24]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:25]=1)([CH3:17])([CH3:18])[CH3:19]

참가 물질

4

반응물 2

HCID 6195839,9-Dichloro-9-silafluoreneHCID 69683378Lithium 4-(3',5'-di-t-butylphenyl)-2-isopropylindene

생성물 1

HCID 220230714-(3',5'-Bis-[t-butyl]phenyl)2-isopropylindene

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

9,9-Dichloro-9-silafluorene (1.1 g, 8.5 mmol) was dissolved in 80 mL of THF. To this solution was slowly added lithium 4-(3′,5′-di-t-butylphenyl)-2-isopropylindene (3.0 g, 8.5 mmol) as a dry powder and the solution was stirred overnight. After this time, the solvent was removed in vacuo and the residue was taken up in diethyl ether. The solution as filtered through frit to remove LiCl and the solvent was removed in vacuo and used as a crude product (3.9 g) for the next step.

후처리

  1. customAfter this time, the solvent was removed in vacuo
  2. filtrationThe solution as filtered through frit
  3. customto remove LiCl
  4. customthe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-1cb234a282444b729e89cc7e79d5109e
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06380123B1

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