Benzoyl chloride, 3,4-dichloro- → HCID 22611642, 화합물

반응식

[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[Cl:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][C:27]=1[Cl:28])[C:22](Cl)=[O:23]>>[Cl:18][C:19]1[CH:20]=[C:21]([CH:25]=[CH:26][C:27]=1[Cl:28])[C:22]([NH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1)=[O:23]

참가 물질

반응물 2

HCID 76403Benzoyl chloride, 3,4-dichloro-

HCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

생성물 1

HCID 22611642HCID 22611642, 화합물수율 82%

실험 절차

Beginning with 10 mg (0.0437 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 9.6 mg (0.0458 mMol) 3,4-dichlorobenzoyl chloride, 14.4 mg (82%) of the title compound were recovered.

출처 및 근거

ORD 기록: ord-8ab66ff997d14a7885b1676d5dc224d1
출처 데이터셋: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06380201B1

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