4-methoxythiophene-3-carboxylic acid → HCID 22611498, 화합물

반응식

[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:11]1[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]1.[CH3:18][O:19][C:20]1[C:21]([C:25](O)=[O:26])=[CH:22][S:23][CH:24]=1>>[CH3:18][O:19][C:20]1[C:21]([C:25]([NH:1][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][CH:6]=[C:5]3[CH:11]2[CH2:16][CH2:15][N:14]([CH3:17])[CH2:13][CH2:12]2)=[O:26])=[CH:22][S:23][CH:24]=1

참가 물질

반응물 2

HCID 27783794-methoxythiophene-3-carboxylic acid

HCID 118312203-(1-Methylpiperidin-4-yl)-1h-indol-5-amine

생성물 1

HCID 22611498HCID 22611498, 화합물수율 109.2%

실험 절차

Beginning with 7.0 mg (0.03 mMol) 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole and 14.2 mg (0.09 mMol) 4-methoxy-3-thienoic acid, 12.1 mg of the title compound were recovered.

출처 및 근거

ORD 기록: ord-07c164b63c1342c3b22e31ef1d319f4b
출처 데이터셋: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06380201B1

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