Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 1-Phenylimidazolidine-2-thione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | 1,2-Ethanediamine, N1-phenyl- | HCID 74270 | — |
| 반응물 | 1,1'-Thiocarbonyldiimidazole | HCID 80264 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-Phenylimidazolidine-2-thione | HCID 12269108 | 35.3% |
반응 단계
1,1′-Thiocarbonyldiimidazole (4.51 g, 25.3 mmol) was added to a solution of N-phenylethylenediamine (3 mL, 23.02 mmol) in THF (230 mL) and the mixture was stirred for 2 h at room temperature. DCM was added and the solution was washed with 1N HCl, dried over anhydrous sodium sulfate and concentrated under reduced pressure affording title compound 301 (1.45 g, 8.13 mmol, 35.3% yield). m/z: 179.1 (M+H)+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846927B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-092dbad1ebed4eb6801116afed0aba82 |
| 출처 메모 | uspto-grants-2014_09 |