HCID 22612300, 화합물 → 3-(1H-tetrazol-1-yl)phenol

HRID 843987노트

반응식

HRID 843987 반응식
C([O:8][C:9]1[CH:10]=[C:11]([N:15]2[CH:19]=[N:18][N:17]=[N:16]2)[CH:12]=[CH:13][CH:14]=1)C1C=CC=CC=1>C(O)C.[Pd]>[N:15]1([C:11]2[CH:10]=[C:9]([OH:8])[CH:14]=[CH:13][CH:12]=2)[CH:19]=[N:18][N:17]=[N:16]1

참가 물질

4

반응물 1

HCID 22612300HCID 22612300, 화합물

생성물 1

HCID 8561923-(1H-tetrazol-1-yl)phenol수율 88.4%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution 1-(3-Benzyloxy-phenyl)-1H-tetrazole (0.640 grams, 2.54 mmole) in ethanol (15 ml) was added 10% palladium on carbon (˜0.100 g). This was stirred under hydrogen balloon over night. The catalyst was removed by filtration, and the solution was concentrated to give a white solid (0.364 g). M.P. 171-172° C.; MW 162.12; MS (m/e) 163 (M++1).

후처리

  1. customThe catalyst was removed by filtration
  2. concentrationthe solution was concentrated

출처 및 근거

ORD 기록
ord-7cee0a2b5c1d42d6a4a23305cd52ffdb
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06380218B1

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