Isopropanol → N-(4-(1-Hydroxy-1-methyl-ethyl)-cyclohexylmethyl)-2-(3-methyl-benzo(d)-isoxazol-5-yloxy)-nicotinamide
반응식
[CH3:1][C:2]1[C:6]2[CH:7]=[C:8]([O:11][C:12]3[N:20]=[CH:19][CH:18]=[CH:17][C:13]=3[C:14]([OH:16])=O)[CH:9]=[CH:10][C:5]=2[O:4][N:3]=1.[CH3:21][CH:22]([OH:24])[CH3:23]>>[OH:24][C:22]([CH:9]1[CH2:8][CH2:7][CH:6]([CH2:2][NH:3][C:14](=[O:16])[C:13]2[CH:17]=[CH:18][CH:19]=[N:20][C:12]=2[O:11][C:8]2[CH:9]=[CH:10][C:5]3[O:4][N:3]=[C:2]([CH3:1])[C:6]=3[CH:7]=2)[CH2:5][CH2:10]1)([CH3:23])[CH3:21]참가 물질
3
실험 절차
Prepared from 2-(3-Methyl-benzo-(d)isoxazol-5-yloxy)-nicotinic acid and trans-2-Aminomethyl-cyclohexyl)-propan-2-ol. mp 135-7° C.
출처 및 근거
- ORD 기록
- ord-8f5dfc9726b04c49aebecba6dedead3a
- 출처 데이터셋
- uspto-grants-2002_04
- 특허 번호
- US06380218B1
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