Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tributylstannane → 4-Benzoyloxy-1-(2-hydroxycyclohexyloxy)-2,2,6,6-tetramethylpiperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tributylstannane | HCID 5948 | — |
| 반응물 | Heptane | HCID 8900 | — |
| 반응물 | 2-Bromocyclohexanol | HCID 266411 | — |
| 반응물 | 1-Hydroxy-4-benzoyloxy-2,2,6,6-tetramethylpiperidine | HCID 688178 | — |
| 용매 | Chlorobenzene | HCID 7964 | — |
| 용매 | Ethylacetate heptane | HCID 21899848 | — |
| 생성물 | 4-Benzoyloxy-1-(2-hydroxycyclohexyloxy)-2,2,6,6-tetramethylpiperidine | HCID 22507645 | — |
반응 단계
Tributyltin hydride is added dropwise to a solution of 2-bromocyclohexanol and excess 4-benzoyloxy-1-oxyl-2,2,6,6-tetramethylpiperidine in chlorobenzene. The mixture is heated to facilitate reaction. The crude reaction mixture is passed through silica gel with heptane and then heptane/ethyl acetate to afford the title compound as a mixture of cis/trans isomers.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06380389B2 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-fd22f4a9462844de866acc785faeb917 |
| 출처 메모 | uspto-grants-2002_04 |