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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 84527생성일: 2026년 10월 25일

1-Amino-2-propanol → N-(2-chloro-4-(2-hydroxypropylcarbamoyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide

https://huagongshe.com/reaction/84527

반응식

참여 물질

역할이름HCID투입량
반응물1-Amino-2-propanolHCID 4—
반응물3-Chloro-4-(N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoic acidHCID 66868923—
생성물N-(2-chloro-4-(2-hydroxypropylcarbamoyl)phenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamideHCID 57900244—

반응 단계

3-Chloro-4-(N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamido)benzoic acid and 1-aminopropan-2-ol were reacted by a procedure similar to that to prepare 137 in Example 47 to give 227. MS: (ESI+) 471.1

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08846762B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-a218e2e3a6c941bfb121d0570f86eaf7
출처 메모uspto-grants-2014_09