2H-Azepin-2-one, 3-aminohexahydro- → Tert-butyl 2-(3-amino-2-oxoazepan-1-yl)acetate

HRID 845331

반응식

HRID 845331 반응식
[NH2:1][CH:2]1[CH2:8][CH2:7][CH2:6][CH2:5][NH:4][C:3]1=[O:9].I[CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13]>>[C:15]([O:14][C:12]([CH2:11][N:4]1[CH2:5][CH2:6][CH2:7][CH2:8][CH:2]([NH2:1])[C:3]1=[O:9])=[O:13])([CH3:18])([CH3:17])[CH3:16]

참가 물질

3

반응물 2

HCID 1024632H-Azepin-2-one, 3-aminohexahydro-HCID 11021060Tert-butyl 2-iodoacetate

생성물 1

HCID 20132368Tert-butyl 2-(3-amino-2-oxoazepan-1-yl)acetate

실험 절차

3-Aminoperhydro-2-azepinone (R. Pellegata, et al., Synthesis, 1978, 614-616) was alkylated with t-butyl iodoacetate as described in Example 1, Step B, to afford 1-t-butoxycarbonylmethyl-3-aminoperhydro-2-azepinone.

출처 및 근거

ORD 기록
ord-7894c250de9d49899b9da1c9725b1850
출처 데이터셋
uspto-grants-1988_07
특허 번호
US04757068

연결된 노트

불러오는 중…