HCID 19014057, 화합물 → HCID 19014054, 화합물
반응식
C([CH:5]([C:17]([OH:19])=[O:18])[O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)(C)(C)C>FC(F)(F)C(O)=O>[C:17]([CH2:5][O:6][C:7]1[CH:8]=[C:9]([CH2:13][C:14](=[O:16])[CH3:15])[CH:10]=[CH:11][CH:12]=1)([OH:19])=[O:18]참가 물질
3
실험 절차
To m-(t-butylcarboxymethoxy)phenyl acetone, 6.7 g, was added trifluoroacetic acid (40 ml) at room temperature under nitrogen. After five minutes, reaction was found to be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride) and the solvent was then evaporated to dryness. The resulting brown oil showed the desired product and trace of starting material on tlc. IR showed characteristic carboxylic acid peak at 3600-2450 cm-1.
후처리
- customreaction
- washto be completed by tlc (silica gel eluted with 1:9 parts by volume methanol:methylene chloride)
- customthe solvent was then evaporated to dryness
출처 및 근거
- ORD 기록
- ord-42c009f3d0b44032b09f074e36fbecbc
- 출처 데이터셋
- uspto-grants-1992_08
- 특허 번호
- US05135863
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