Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → Triphenylphosphine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | HCID 178514248 | HCID 178514248 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Triphenylphosphine | HCID 11776 | — |
| 생성물 | Oxazoline | HCID 68157 | — |
반응 단계
Hydroxyamide IX is then subjected to cyclodehydration in an inert organic solvent (e.g., tetrahydrofuran, acetonitrile or chloroform) under an inert atmosphere (e.g., argon) with triphenylphosphine (employing a molar ratio of V:triphenylphosphine of from about 0.8:1 to about 1:1) and carbon tetrachloride in the presence of an amine base (e.g., triethylamine or diisopropylethylamine) to form oxazoline ##STR23##
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05135939 |
| 출처 데이터셋 | uspto-grants-1992_08 |
| ORD ID | ord-9faeadff4ef440cda5bbff849c7c2f54 |
| 출처 메모 | uspto-grants-1992_08 |