4-Hydroxybenzaldehyde → 2-(Hexyloxy)benzaldehyde
반응식
CN([CH:4]=[O:5])C.C(=O)([O-])[O-].[K+].[K+].[OH:12][C:13]1[CH:20]=[CH:19][C:16](C=O)=[CH:15][CH:14]=1.[CH2:21](Br)[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>O>[CH2:21]([O:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:19][C:20]=1[CH:4]=[O:5])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]참가 물질
6
실험 절차
To 250 ml of DMF containing 207 g of anhydrous potassium carbonate (1.5M) was added 122 g of 4-hydroxybenzaldehyde and 181.6 g of hexylbromide. The resultant mixture was heated at reflux temperature overnight after which it was poured into cold water and extracted with ethylacetate. The extracts were dried and evaporated in vacuo to afford the desired subtitled intermediate (80% yield), b.p. 110°-115° C.
후처리
- temperatureat reflux temperature overnight after which it
- extractionextracted with ethylacetate
- customThe extracts were dried
- customevaporated in vacuo
출처 및 근거
- ORD 기록
- ord-15d173bb53d647d288e8eb7dc4418afe
- 출처 데이터셋
- uspto-grants-1992_08
- 특허 번호
- US05135955
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