Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → 4-[4-(Hexyloxy)phenyl]-3-(4-methoxyphenyl)-2-butanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| 반응물 | p-(Hexyloxy)benzaldehyde | HCID 79816 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 4-[4-(Hexyloxy)phenyl]-3-(4-methoxyphenyl)-2-butanone | HCID 19885147 | 46% |
반응 단계
49.2 g of 3-(4-methoxyphenyl)-2-propanone and 61.8 g of 4-hexyloxybenzaldehyde were added to 100 ml of toluene containing 4 ml of piperidine. The resultant mixture was heated at reflux temperature overnight after which the solvent was removed in vacuo to afford the desired subtitled intermediate (46% yield), b.p. 230°-235° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05135955 |
| 출처 데이터셋 | uspto-grants-1992_08 |
| ORD ID | ord-19e7f61cde12489b985d8cc75dfc7d32 |
| 출처 메모 | uspto-grants-1992_08 |