참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Iodododecane | HCID 20282 | — |
| 반응물 | Trilauryl phosphite | HCID 76495 | — |
| 반응물 | Benzenemethanamine,N-(phenylmethylene)-, N-oxide | HCID 305634 | — |
| 생성물 | Didodecyl P-[alpha-(N-Benzyl-N-dodecyloxyamino)benzyl]phosphonate | HCID 19883773 | 28% |
반응 단계
A mixture of 5.0 g (23 mmol) of N-benzylidenebenzylamine N-oxide, 17.6 g (30 mmol) of tri-n-dodecyl phosphite and 29.6 g (100 mmol) of n-dodecyl iodide is heated at 70° C. for 24 hours. The reaction mixture is concentrated in vacuo and the residue is purified by HPLC (4:1 hexane:ethyl acetate eluent) followed by flash chromatography (methylene chloride eluent) to give 5.1 g (28% yield) of the title compound as a white solid melting at 38°-40° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05137951 |
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| 출처 데이터셋 | uspto-grants-1992_08 |
|---|
| ORD ID | ord-71e59d075909419a9e13862f78d94d78 |
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| 출처 메모 | uspto-grants-1992_08 |
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