Benzene → HCID 14010457, 화합물

HRID 847122노트

반응식

HRID 847122 반응식
C1C=CC=CC=1.[Cl:7][C:8]1[CH:18]=[C:17]([Cl:19])[C:16]([Cl:20])=[CH:15][C:9]=1[O:10][CH2:11][C:12](Cl)=[O:13].[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1>C(N(CC)CC)C>[Cl:7][C:8]1[CH:18]=[C:17]([Cl:19])[C:16]([Cl:20])=[CH:15][C:9]=1[O:10][CH2:11][C:12]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1)=[O:13]

참가 물질

5

반응물 3

HCID 241BenzeneHCID 104392-AminopyridineHCID 3027592,4,5-trichlorophenoxyacetyl chloride

생성물 1

HCID 14010457HCID 14010457, 화합물

시약·촉매·용매 1

HCID 8471Triethylamine용매

실험 절차

After filling in a dry 250 ml flask respectively 150 ml of anhydrous benzene and 32.5 g (0.118 mol) of 2,4,5-trichlorophenoxyacetyl chloride synthesized in Example 14, 11 g (0.118 mol) of 2-aminopyridine was added with vigorous stirring, and then 8.1 ml of triethylamine was slowly dropped to be heated and refluxed for 2-3 hours, while the external temperature was maintained at 80°-90° C.

후처리

  1. customAfter filling in a dry 250 ml flask
  2. temperatureto be heated
  3. temperaturerefluxed for 2-3 hours, while the external temperature
  4. temperaturewas maintained at 80°-90° C.

출처 및 근거

ORD 기록
ord-db21de2a82c141c79b165d338e6f47a1
출처 데이터셋
uspto-grants-1992_08
특허 번호
US05139564

반응 노트

불러오는 중…