4-((Dimethylamino)methyl)benzonitrile → HCID 19881402, 화합물

HRID 847414노트

반응식

HRID 847414 반응식
[CH:1]1[C:18]2[C:5](=[C:6]([C:19]3[CH:26]=[CH:25][CH:24]=[CH:23][C:20]=3[CH2:21][Br:22])[C:7]3[C:16]([CH:17]=2)=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[CH3:27][N:28]([CH2:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]#[N:38])=[CH:33][CH:32]=1)[CH3:29].[PH4+].[AsH4+]>C(#N)C.C(OCC)C>[Br-:22].[C:37]([C:34]1[CH:33]=[CH:32][C:31]([CH2:30][N+:28]([CH2:21][C:20]2[CH:23]=[CH:24][CH:25]=[CH:26][C:19]=2[C:6]2[C:7]3[C:16](=[CH:15][C:14]4[C:9]([CH:8]=3)=[CH:10][CH:11]=[CH:12][CH:13]=4)[CH:17]=[C:18]3[C:5]=2[CH:4]=[CH:3][CH:2]=[CH:1]3)([CH3:27])[CH3:29])=[CH:36][CH:35]=1)#[N:38]

참가 물질

7

반응물 4

HCID 8263294-((Dimethylamino)methyl)benzonitrileHCID 5460504PhosphoniumHCID 5460506ArsoniumHCID 19881404HCID 19881404, 화합물

생성물 1

HCID 19881402HCID 19881402, 화합물

시약·촉매·용매 2

HCID 3283Diethyl Ether용매HCID 6342Acetonitrile용매

실험 절차

A mixture of (B) and N,N-dimethyl-4-cyano benzylamine in acetonitrile was refluxed for 2 hours. The reaction mixture was then poured into diethyl ether, and the crude product was collected by filtration. The crude product was recrystallized from ethanol. The same reaction can be used to prepare the corresponding phosphonium and arsonium salts.

후처리

  1. temperaturewas refluxed for 2 hours
  2. filtrationthe crude product was collected by filtration
  3. customThe crude product was recrystallized from ethanol
  4. customThe same reaction

출처 및 근거

ORD 기록
ord-c99f46cb7eb8477eb0e8a2917d7c6568
출처 데이터셋
uspto-grants-1992_08
특허 번호
US05141969

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